Sunday, August 26, 2007

氨基酸

小题一下:网上看到某强人说××在某大学获得博士学位继而在何处有获得博士后学位,挺奇怪的,我只知道勇士死后可以晋级成烈士,也没听过有勇士后的荣誉。。可能外国的月亮和我们不一样,也可能指的post dr就是像house那样的在社会大学才能取得的吧。不然cuddy早把他炒了。

氨基酸名字的来源,我看到了很猥琐的一个记忆方法,老实说可能只适合作者本人。英语来源的词汇参考说英语的人的记忆方法,肯定会有帮助。于是google origin of aminio acid name
The origin of the single-letter code for the amino acids
这是single-letter origin(中文字和字母对表达英语的word,letter要区别挺麻烦的)。
众所周知,英语单词,特别是社会科学不是凭空找出来的,都是从词根加工过来排列组合而成,而且记忆词根对英语学习绝对不是负担,所以就当是学英语的一个课外读物吧。对那个猥琐的中文记法标识鄙视。

摘录如下:
The listing of amino acids, the three letter and single letter code, and the explanation for the choice of the single letter is given below. Note that there are 20 amino acids commonly found in proteins, and 26 letters in the alphabet. As a result, most of the letters are used.

To develop a single-letter code for the amino acids, Dr. Dayhoff attempted to make the code as easy to remember as possible. Of course, if the name of each amino acid began with a different letter, the code would be simple indeed. (双螺旋结构里,watson讲述他们开办的氨基酸俱乐部,至今还没看到过他们公开俱乐部人员各自领带上写的是那一种氨基酸,watson好像是精氨酸)

For 6 of the amino acids, the first letter of the name is unique, making the code simple. These are:

Amino Acid
3 letter code
Single letter code
Explanation

Cysteine
Histidine
Isoleucine
Methionine
Serine
Valine

Cys
His
Ile
Met
Ser
Val
C
H
I
M
S
V
First letter of the name
First letter of the name
First letter of the name
First letter of the name
First letter of the name
First letter of the name

For the other amino acids, the first letter of the name is not unique to a single amino acid, so Dr. Dayhoff assigned the letters A, G, L, P and T to the amino acids Alanine, Glycine, Leucine, Proline and Threonine, respectively, which occur more frequently in proteins than do the other amino acids having the same first letters.

Amino Acid
3 letter code
Single letter code
Explanation
Alanine
Glycine
Leucine
Proline
Threonine
Ala
Gly
Leu
Pro
Thr
A
G
L
P
T
First letter of the name
First letter of the name
First letter of the name
First letter of the name
First letter of the name

Some of the other amino acids are phonetically suggestive.

Amino Acid
3 letter code
Single letter code
Explanation
Arginine
Phenylalanine
Tyrosine
Tryptophan
Arg
Phe
Tyr
Trp
R
F
Y
W

aRginine
Fenylalanine
tYrosine
tWiptophan (or, contains Double ring)

For the remaining 5 amino acids, Dr. Dayhoff was reaching somewhat to find an easy-to-remember connection between the single letter and the amino acid. She assigned aspartic acid, asparagine, glutamic acid and glutamine the letters D, N, E and Q, respectively, noting that D and N are nearer the beginning of the alphabet than E and Q, and that Asp is smaller than Glu, while Asn is smaller than Gln.

Amino Acid
3 letter code
Single letter code
Explanation
Aspartic Acid
Asparagine
Glutamic Acid
Glutamine
Asp
Asn
Glu
Gln

D
N
E
Q

asparDic
Contains N (or asparagiN)
gluE (or glutamEke)
Q-tamine

By the time Dr. Dayhoff got to lysine, there were not too many letters left, so she used the letter K, explaining that K is at least near L in the alphabet.

Amino Acid
3 letter code
Single letter code
Explanation
Lysine
Lys
K

K is near L in the alphabet


single letter的明明人似乎是dr. margaret oakley dahhoff.

Dr. Dayhoff was extremely active in the Biophysical Society, and served the society as both its secretary and president. One of her interests was in enhancing the ability of women to successfully pursue careers in the sciences. She was well aware of the many challenges facing women in science, and worked hard to encourage and mentor women in scientific careers. It is therefore fitting that the Margaret Oakley Dayhoff award was established to encourage young women to enter careers in scientific research. This award is aimed towards women of very high promise who have not yet reached a position of high recognition within the structure of academic society. It is administered through the Biophysical Society , and candidates are judged on achievement and promise in fields within the purvue of the Biophysical Society .


向所有女权运动者致敬。

岁可以把20个氨基酸的词根写一下就好了。

No comments:

Post a Comment